Our new Distinct+ tissue clearing strategy is the one process that delipidates samples with no alter in morphology and with nominal effect on structural integrity.
Megatome is usually a vibrating microtome created to area a wide choice of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With superior blade vibrating frequency and minimized blade deflection, Megatome enables significant-throughput tissue sectioning with uniform area profile, in addition to small tissue destruction and knowledge loss.
Ask for a quotation or demo Uniformly portion large tissues & sample arrays Megatome is the only microtome that can section samples as large as intact nonhuman primate and human organs, rendering it a must have for fields which include neuropathology.
Megatome is made for accuracy: the blade vibrates at a greater frequency and larger amplitude variety than other microtomes, and includes a exceptional deflection Handle mechanism.
SE works by using a rotational electrical discipline to disperse very electromobile molecules (including antibodies or surfactant micelles) all through a porous sample without harming electrically billed structures within the tissue. This permits 2-4 working day clearing of intact organs,
Our preformulated EasyIndex Answer raises and homogenize the refractive index of delipidated tissue samples, rendering them absolutely clear. This permits mild penetration into the sample and makes sure the acquisition of significant-resolution, in-emphasis picture data.
Megatome is usually a novel microtome that enables for high-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with small tissue destruction and data loss.
eFLASH is often a fast megatomi.com tissue labeling system that permits for uniform whole-organ staining in twenty rounds of labeling.
The SmartSPIM light sheet microscope supplies unparalleled resolution and acquisition speed in the course of intact tissue volumes, whilst its modular style and design permits you to enhance and customize unique elements.
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SHIELD avoids the variability of hydrogel embedding and the knowledge reduction from PFA preservation, defending specimens for a number of rounds of processing.
Leverage the Obvious+ tissue clearing process, along with eFLASH and patented stochastic electrotransport technologies, to speedily crystal clear and label full organs. Key highlights and functions incorporate:
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